Cytochrome c oxidase subunit 6B1 pseudogene 7 (COX6B1P7)

Cytochrome c oxidase subunit 6B1 pseudogene 7 (COX6B1P7) is a human processed pseudogene located on chromosome 1p31.3[1][3]. It is homologous to the functional COX6B1 gene, which encodes a subunit of cytochrome c oxidase—an essential component of the mitochondrial electron transport chain responsible for cellular respiration—but COX6B1P7 itself does not encode a functional protein[3][7]. Pseudogenes like COX6B1P7 arise from duplication or retrotransposition events and accumulate disabling mutations, preventing protein production[2][7]. While traditionally considered "junk DNA," research indicates some pseudogenes modulate gene expression, participate in competing endogenous RNA (ceRNA) networks, or influence parental gene regulation, but specific functional or disease roles for COX6B1P7 have not been established[2][6]. Accordingly, it is not classified as an enzyme, receptor, channel, transporter, or a conventional drug target. COX6B1P7 is a processed pseudogene, not a functional protein or therapeutic target, and currently lacks evidence for direct biological function, disease association, or drug interaction[1][2][3][5][7].

Other names

cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) pseudogene 7COX6B1P7