Target intelligence / Profile preview

Cytochrome c oxidase subunit 8C pseudogene

Molecular classification
Pseudogene, Processed pseudogene or duplicated pseudogene (mechanism depends on genomic context)
01

Overview

Cytochrome c oxidase subunit VIIIC pseudogene (ENSG00000275130) is a pseudogene that shows DNA sequence similarity to the functional gene encoding cytochrome c oxidase subunit 8C, a component of complex IV in the mitochondrial electron transport chain, but due to frameshifts, premature stop codons, or other disabling mutations, it does not produce a functional protein. Pseudogenes such as this arise from evolutionary gene duplication or retrotransposition events and typically have no coding or regulatory function, though they may occasionally be transcribed at low levels. This pseudogene does not participate in cellular respiration or energy metabolism, nor is it implicated in disease or used as a biomarker or therapeutic target. In summary, this entry represents a nonfunctional pseudogene with no current biomedical relevance for therapy, biomarker development, or drug discovery. It should not be considered a therapeutic target, and its presence is a result of evolutionary genomic processes.

Other names
COX8C pseudogeneCytochrome c oxidase subunit VIIIC pseudogeneENSG00000275130

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