Cytochrome c pseudogene 10 (CYCSP10)

Cytochrome c pseudogene 10 is one of approximately 49 cytochrome c–related pseudogenes identified in the human genome, systematically named from HCP1 to HCP49, and annotated as CYCSP10 in certain databases[1][2][4]. These pseudogenes result from duplications and mutations of the functional cytochrome c gene (CYCS/HCS)—typically located on chromosome 7—and are scattered across different chromosomes[1][2]. CYCSP10 is specifically classified as a **pseudogene**, meaning that it resembles the functional cytochrome c gene at the DNA sequence level but generally does not encode a functional protein due to disabling mutations, truncations, and lack of expression evidence[1][2][4]. It is not a **therapeutic target** such as a receptor, enzyme, transporter, or transcription factor[4]. There is **nothing suggesting an active biological role or drug interaction; no protein product, receptor activity, or enzyme function is reported**[1][2][4]. Its presence as a pseudogene indicates **no known disease association** or utility as a biomarker, drug target, or source of safety concern[4]. The designation "CYCS pseudogene 10" or its alias "HCP10" refers to its sequence similarity to *cytochrome c*, an essential mitochondrial protein, but CYCSP10 itself is non-functional[1][2][4]. The existence of CYCSP10 is due to **genomic duplication events**, and it is classified as a pseudogene based on lack of introns, frameshifts, premature stop codons, and absence of detectable expression[1][2]. In practical terms, **CYCSP10 is not a molecular target** for drugs, diagnostics, or research in the conventional sense. Its annotation is mostly of interest for genomic mapping, evolutionary studies, or in the context of pseudogene biology.

Other names

HCP10CYCS pseudogene 10CYCSP10