Cytochrome c pseudogene 12 (CYCSP12)

Cytochrome c pseudogene 12 (CYCSP12), also designated as HCP12 or HCP13, is one of a group of cytochrome c processed pseudogenes distributed throughout the human genome. It lacks both introns and the ability to encode a functional protein, as it contains multiple sequence disablements (frameshifts, stop codons) and is not known to be expressed. As a pseudogene, it is a non-functional genomic sequence homologous to the cytochrome c gene (HCS), and serves no known biological role. It is not used as a drug target, biomarker, or therapeutic agent, and there is no evidence of involvement in disease or normal physiology. The human genome contains a single functional cytochrome c gene and numerous pseudogenes (HCP1–HCP49), which are named based on chromosomal location and homology; HCP12 and HCP13 are specific entries in this series. CYCSP12/HCP12 does not possess coding capacity and shows no evidence of RNA or protein product. Pseudogenes such as CYCSP12 are non-functional, do not have a role in cellular processes, and are not regarded as drug targets or biomarkers. No evidence links CYCSP12/HCP12/HCP13 to any disease, drug interaction, or mechanism of action. Its designation is sometimes confused, and the lack of function makes it an invalid target for therapeutic or diagnostic purposes. Cytochrome c pseudogenes are sometimes mistakenly included in gene or protein panels, but do not represent actual protein-coding genes or valid therapeutic targets. This makes CYCSP12 (HCP12, HCP13) an incorrect or irrelevant target in drug discovery and biomedical applications.

Other names

HCP12HCP13