Cytochrome P450 family 2 subfamily A member 7 pseudogene 1 (CYP2A7P1)

Cytochrome P450 family 2 subfamily A member 7 pseudogene 1 (CYP2A7P1) is a nonfunctional genomic sequence that shares high homology with active cytochrome P450 genes but contains disabling mutations prohibiting the production of a functional protein. It is considered a processed or unprocessed pseudogene and is not involved in xenobiotic metabolism or drug interactions. Pseudogenes like CYP2A7P1 may play regulatory roles in gene expression via RNA-based mechanisms but are generally not therapeutic drug targets or known to be directly implicated as causative in human disease. Key Notes: - This is a pseudogene, meaning it is a DNA sequence similar to a functional gene (CYP2A7), but it is not transcribed or translated into an active, functional enzyme. - Pseudogenes, including CYP2A7P1, may influence gene regulation by acting as competitive endogenous RNA (ceRNA) or miRNA decoys but do not produce proteins with direct therapeutic interest. - There is no evidence that CYP2A7P1 interacts with drugs or serves as a therapeutic target. - There is no evidence that CYP2A7P1 is used as a biomarker or is associated with specific adverse safety considerations. - CYP2A7P1, as a pseudogene, may be relevant in genomics research (e.g., complicating variant calling or functional genomics studies due to sequence similarity with the parent gene). - Multiple aliases refer to the same pseudogene in the literature, often as result of annotation changes and confusion with similar pseudogenes.

Other names

CYP2A18PNCYP2A7PTCYP2A18PCCYP2A7P2cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 2cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7, pseudogene 1cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 7, pseudogene 2