Cytokine Signaling Pathways in Immune Cells in Skin Tissue

Cytokine signaling pathways in immune cells within skin tissue constitute a complex network regulating both innate and adaptive immune responses. These pathways involve cytokines (e.g., IL-1α, TNF-α, IL-10), their receptors, intracellular signaling cascades (primarily JAK/STAT), and regulatory proteins like SOCS. Dysregulation is implicated in inflammatory skin diseases like psoriasis and atopic dermatitis, making them attractive therapeutic targets.

Other names

Cutaneous Cytokine NetworkSkin Immune SignalingCytokine-Mediated Inflammation in Skin

Modulation of cytokine receptor interactions or intracellular signaling cascades (e.g., JAK/STAT pathway) to alter gene expression and immune cell function.