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Target intelligence / Profile preview
Cytosolic Phospholipase A2α (cPLA2α)
- Target
- cPLA2α
- Molecular classification
- Hydrolase
01
Overview
Releases arachidonic acid from membrane phospholipids, providing substrate for downstream leukotriene synthesis
02
Mechanism of action
Inhibition of arachidonic acid release
03
Biological functions
Releases arachidonic acid from phospholipidsLipid metabolism
04
Disease associations
AsthmaAllergic rhinitisAnaphylaxisInflammation
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