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D4, zinc and double PHD fingers family 2 pseudogene (ENSG00000218857, LOC100421246, also known as AL137222.1) is a human pseudogene with sequence similarity to the DPF2 gene. As a pseudogene, it does not produce a functional protein product and is not considered a viable molecular or therapeutic target. The functional DPF2 gene encodes a zinc finger-containing transcription factor associated with apoptosis and hematopoietic cell regulation[1][2][3][6][7]. The DPF2 protein is involved in chromatin remodeling and transcriptional regulation, but this pseudogene has no confirmed biological activity, disease association, or relevance for drug discovery or biomarker development.\n\nNote: \n- This entry is **not a functional gene, receptor, or target**, but rather a pseudogene likely included due to similarity to the active DPF2 gene. If a functional chromatin regulatory target is sought, refer to the canonical DPF2 gene/protein (BAF45D, apoptosis response zinc finger protein)[6][7]. \n- There is **nothing inherently misspelled** or structurally incorrect about the entry itself, but **pseudogenes are not considered actionable or druggable targets** in current therapeutic paradigms[2].\n- The DPF2 gene (not the pseudogene) encodes a zinc finger protein and transcription factor involved in cell death and regulation, but **ENSG00000218857 is not the active gene**[6][7].
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