Dactylis glomerata pollen allergens

Dactylis glomerata pollen allergens are extracts from the pollen of the orchard grass (Dactylis glomerata) plant, primarily used in diagnostic testing and immunotherapy for grass pollen allergies. These allergens, including specific proteins like Dac g 3 and Dac g 4, trigger IgE-mediated immune responses leading to allergic rhinitis with or without conjunctivitis in sensitized individuals. They are key components in products like Oralair and standardized grass pollen extracts, approved for sublingual or injection use in patients aged 5-65 with confirmed sensitivity via skin tests or IgE assays. Poaceae family pollen allergens like these are classified by protein structure and function, contributing to seasonal allergies from atmospheric exposure. While not traditional therapeutic targets like receptors or enzymes, they serve as antigens in allergen-specific immunotherapy to induce tolerance and reduce symptoms. Safety concerns include heightened hypersensitivity risks when combined with certain drugs like beta-blockers.

Other names

Dactylis glomerata pollenorchard grass pollen extractcocksfoot grass pollenstandardized orchard grass pollenallergenic extract- orchard grass dactylis glomerata