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Damaged myocardium refers to injury or death of the heart muscle (myocardium), most commonly resulting from insufficient blood supply (ischemia) due to blockage or narrowing of the coronary arteries. This damage can be acute, as in myocardial infarction (heart attack), or chronic, as seen in conditions like hibernating myocardium. Damaged myocardium is not a direct drug target; instead, therapeutic interventions aim to limit further damage, restore blood flow, and manage the consequences of the damage.
Varied, depending on the cause and drug. Examples include: reducing thrombus formation, lowering cholesterol, reducing blood pressure, blocking adrenergic receptors.
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