DDB1 and CUL4 associated factor 6 pseudogene

**DDB1 and CUL4 associated factor 6 pseudogene** (ENSG00000259299; LOC100420707) is a non-protein-coding genomic locus annotated as related to the DCAF6 gene, which encodes a WD-repeat-containing protein and functions as a coactivator for nuclear receptors in its protein-coding form[1][3][5]. However, as a pseudogene, ENSG00000259299 does not produce functional protein and lacks defined molecular function, clinical roles, or therapeutic relevance.\n\n**Key distinctions:**\n- The functional, protein-coding version is DCAF6 (HGNC: 30002, ENSG00000143164), whereas ENSG00000259299 refers specifically to the pseudogene form and is not a receptor, enzyme, transporter, or other druggable target[2][3][5].\n- No evidence supports therapeutic targeting, involvement in disease biology, biomarker utility, safety concerns, or known drug interactions for this pseudogene[3][5][6].\n\n**Summary:**\nENSG00000259299/LOC100420707 is a pseudogene and not an active molecular target for drug discovery or biomarker development. For structured information on the protein-coding version, consult resources for DCAF6 (ENSG00000143164)[2][5].

Other names

DCAF6 pseudogeneLOC100420707RP11-37J13.1 processed pseudogene