DDR1 divergent transcript (DDR1-DT)

**DDR1 divergent transcript (DDR1-DT)** is a non-coding RNA gene located in the vicinity of the DDR1 gene on chromosome 6p21.33[3][7]. It is also called DDR1-AS1 (DDR1 antisense RNA 1), TIGD1L, bPG70P20.2, bCX111D4.7, and bQB10J12.1[1][3]. Unlike the protein-coding DDR1 gene, which encodes the discoidin domain receptor 1 — a receptor tyrosine kinase involved in collagen signaling, cell adhesion, and tumor biology[2][4][5][6][8] — DDR1-DT is not known to encode a functional protein and is not considered a therapeutic target. Its biological function is not described in the current scientific literature, and it has no established role as a disease gene, biomarker, or drug target[7]. **Key clarification:** - **DDR1 divergent transcript (DDR1-DT)** should not be conflated with **DDR1 (Discoidin domain receptor 1)**, which is a validated receptor tyrosine kinase and recognized oncology drug target[4][5][8]. - There is no evidence that DDR1-DT is a receptor, enzyme, transporter, or other classical drug target.

Other names

bPG70P20.2bCX111D4.7bQB10J12.1TIGD1LDDR1-AS1

None known; not a protein or enzyme, so no mechanism of action for drug interaction is described.