Target intelligence / Profile preview

DDX25 antisense RNA 1 (DDX25-AS1)

Target
DDX25-AS1
Molecular classification
Antisense long noncoding RNA, lncRNA, Other
01

Overview

DDX25 antisense RNA 1 (DDX25-AS1) is a long noncoding RNA (lncRNA) gene transcribed antisense to the protein-coding gene DEAD-box helicase 25 (DDX25)[1][6]. Antisense lncRNAs typically regulate the expression of their sense gene counterparts by various mechanisms, including modulation of RNA stability, epigenetic modifications, or formation of RNA duplexes, though the specific function of DDX25-AS1 in human biology is not yet characterized in detail[2][6]. No scientific data currently identify DDX25-AS1 itself as a direct therapeutic target, nor are there drugs documented to act on this molecule. The full spectrum of its roles, interacting molecules, and therapeutic relevance remain to be determined. Note: - Information on DDX25-AS1 itself is limited; DDX25, the sense gene, is a well-characterized ATP-dependent RNA helicase involved in spermatogenesis, but this should not be confused with DDX25-AS1, which is a noncoding RNA transcribed from the opposite strand[3][5][7]. - No major errors or misspellings were found for this gene symbol and name, and it matches entries in authoritative gene databases[6][1].

Other names
DDX25-AS1long noncoding RNA DDX25-AS1
02

Biological functions

Regulation of gene expressionLikely RNA stability and/or epigenetic regulation (by analogy to other antisense lncRNAs)
03

Disease associations

Unknown (no specific disease roles for DDX25-AS1 identified in major databases or literature as of now. However, antisense lncRNAs as a class often play roles in cancer and gene regulation)

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