DDX3 interacting long non-coding RNA 1 (DDX3ILA1)

DDX3 interacting lncRNA 1 (DDX3ILA1, also known as TCONS_00012883) is a long non-coding RNA identified in humans and located on chromosome 22[1]. LncRNAs like DDX3ILA1 do not encode proteins but act as molecular scaffolds or regulators, often influencing gene expression and cellular processes[2][6][8]. Specifically, DDX3ILA1 is reported to promote proliferation and metastasis in colorectal cancer through interaction with proteins such as DDX3, YY1, and the PI3K-AKT signaling axis[3][7]. Though it is biologically significant and disease-relevant, it is not conventionally classified as a direct therapeutic target, receptor, enzyme, or transporter[5][7]. Current evidence does not link DDX3ILA1 to any approved drug interactions or use as a clinical biomarker.

Other names

TCONS_00012883