DEAD-box helicase 18 pseudogene 3 (DDX18P3)

DDX18P3 is classified as a pseudogene, meaning it is a genomic sequence similar to the protein-coding gene *DEAD-box helicase 18 (DDX18)* but is generally non-functional and does not encode a functional protein[3]. The canonical DDX18 gene encodes an ATP-dependent RNA helicase involved in RNA metabolism, including ribosome biogenesis, R-loop homeostasis, and pluripotency regulation[1][3]. Pseudogenes may arise from gene duplication or retrotransposition events, and their transcripts, if expressed, typically do not result in functional proteins or participate in known biological pathways or therapeutic mechanisms[3]. There is no established evidence of DDX18P3 functioning as a receptor, enzyme, transporter, or therapeutic target, nor does it have validated roles in disease, drug interaction, biomarker usage, or safety concerns. As a result, DDX18P3 should not be considered a therapeutic target or functional molecule by current scientific standards. If you intended the protein-coding gene **DEAD-box helicase 18 (DDX18)**, that molecule is a biologically active ATP-dependent RNA helicase implicated in ribosome biogenesis and gene regulation, and is associated with Bloom syndrome and pluripotency in embryonic stem cells[1][3]. However, DDX18P3 refers specifically to a pseudogene, not the functional DDX18 protein[3]. If more information about the functional DDX18 gene or corrections to the name are desired, please specify.

Other names

DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 pseudogene 3DDX18P3