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DEAD-box helicase 18 pseudogene 6 (DDX18P6) is annotated as a pseudogene in the human genome. Pseudogenes are DNA sequences that resemble functional genes but lack the ability to encode proteins due to mutations, deletions, or disruptions in their coding sequence and regulatory elements[1]. DDX18P6 corresponds to the functional DEAD-box helicase 18 gene (DDX18), which is an ATP-dependent RNA helicase involved in RNA unwinding, ribosome biogenesis, and maintaining genomic stability[4]. Unlike DDX18, DDX18P6 does not produce a protein or participate in biological processes and is not considered a therapeutic target, receptor, enzyme, transporter, or biomarker[1]. There is no evidence that DDX18P6 interacts with drugs or is related to disease phenotypes.
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