DEAD-box helicase 3 pseudogene 3 (DDX3P3)

DEAD-box helicase 3 pseudogene 3 (DDX3P3) is a human pseudogene related to the DEAD-box helicase 3 family, specifically to DDX3X and DDX3Y, which are functional RNA helicases involved in RNA metabolism and several biological processes, including translation and immune signaling[1][2][3]. DDX3P3 does not encode a functional protein and has no known biological function, disease relevance, or therapeutic targeting potential. Context and distinction: The actual therapeutically relevant targets in this gene family are DEAD-box helicase 3 X-linked (DDX3X) and DEAD-box helicase 3 Y-linked (DDX3Y), which are ATP-dependent RNA helicases with major roles in RNA metabolism, translation initiation, cell cycle regulation, immune response, and cancer—these are true targets and have been implicated in disease mechanisms and potential drug targeting[1][2][3]. Pseudogenes such as DDX3P3 may be included in genomic studies or listed in annotation databases but are not considered valid therapeutic targets. If your query intends to refer to an *active* helicase, the correct targets would be "DEAD-box helicase 3 X-linked (DDX3X)" or "DEAD-box helicase 3 Y-linked (DDX3Y)"[1][2][3]. For DDX3P3, all actionable or disease-relevant molecular information is not applicable.

Other names

DDX3P3DEAD-box RNA helicase 3 pseudogene 3DEAD-box helicase 3 pseudogene