DEAD box polypeptide 4 pseudogene

DEAD box polypeptide 4 pseudogene (ENSG00000270779) is a non-functional sequence in the human genome homologous to the DEAD-box helicase 4 (DDX4) gene. Pseudogenes generally arise through gene duplication or retrotransposition events that subsequently accumulate disabling mutations, rendering them non-functional and unable to encode active proteins[2][6][7]. While some pseudogenes can play regulatory roles at the RNA level, there is no evidence that this specific pseudogene has biological or clinical significance. It does not act as an enzyme, receptor, transporter, or other classically druggable target, and should not be considered a therapeutic target. Key note: If your intent was to study or target the functional DEAD-box helicase 4 protein (DDX4), which is involved in germ cell development and associated with some diseases such as infertility[1][4], you should refer to DDX4 (Gene: DDX4, Ensembl: ENSG00000152670). The pseudogene entry is not suitable for therapeutic or biomarker applications.

Other names

DDX4 pseudogeneDDX4P