DEAD box polypeptide 60 pseudogene (DDX60P)

The DEAD box polypeptide 60 pseudogene (ENSG00000224436) is a non-functional genomic sequence that shares homology with the DEAD box RNA helicase family, specifically DDX60. DEAD box proteins are essential regulators of RNA metabolism and act as RNA helicases, but pseudogenes do not produce active protein. Pseudogenes are frequently found throughout the human genome and may occasionally be transcribed into RNA, but they lack evidence for direct involvement in cellular signaling, disease mechanisms, or drug interactions[2][4]. The most relevant DEAD box protein, DDX60, is an antiviral factor and nucleic acid sensor, but the pseudogene variant (DDX60P) is not considered a therapeutic target[5][7]. Some transcribed pseudogenes have been implicated in cancer diagnosis and prognosis, potentially serving as biomarkers for specific malignancies, but there is no strong evidence for clinical or functional relevance of this specific pseudogene[2][4].

Other names

DEAD box 60 pseudogeneDDX60PDExD/H box polypeptide 60 pseudogeneENSG00000224436