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Defensin beta 108D (DEFB108D) is a pseudogene in the beta-defensin family. Beta-defensins are small, cationic peptides with antimicrobial activities and roles in innate immune defense, but DEFB108D is classified as a pseudogene without evidence of encoding a functional protein[1]. While beta-defensins in general can play roles in host immunity and antimicrobial activity[2][3][4][5][7][8], there is no evidence linking DEFB108D to a known biological function, disease process, or therapeutic intervention in humans[1].
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