Deleted in esophageal cancer 1 (DELEC1)

Deleted in esophageal cancer 1 is an RNA gene located on chromosome 9q33.1, commonly deleted in esophageal squamous cell carcinomas, with reduced or absent expression in these tumors. It is considered a candidate tumor suppressor gene due to its frequent loss or reduction in expression in multiple cancers. DELEC1 is categorized as a long non-coding RNA (lncRNA) gene and is not confirmed to encode a protein. Current research has not delineated a specific biological function or molecular mechanism, and no established drugs, clinical biomarkers, or safety concerns are documented in relation to this gene. Some literature and database entries inadvertently conflate DELEC1 with DLEC1, which is a protein-coding tumor suppressor involved in cell proliferation and may have different functionalities. If your context is strictly about the DELEC1 gene on chromosome 9 annotated as a non-coding RNA, it is best considered a putative tumor suppressor and not a validated drug target or receptor.

Other names

DELEC1CTS9DEC1Candidate tumor suppressor 9Candidate tumor suppressor CTS9