Dengue virus 1 structural protein

“Dengue virus 1 structural proteins” is a collective term referring to the three main structural proteins found in all dengue viruses, including type 1 (DENV1): the **capsid (C)**, **pre-membrane/membrane (prM/M)**, and **envelope (E)** proteins[4][3]. These proteins form the viral particle: the capsid protein encapsidates the viral RNA and interacts with the lipid membrane; the prM/M protein organizes the outer structure and aids in particle maturation; and the E protein mediates viral attachment, membrane fusion, and is the main antigenic determinant for neutralizing antibodies[4][3][1]. These structural proteins are key in the viral life cycle and represent major therapeutic and vaccine targets[3][4]. Drugs inhibiting their function have shown antiviral effects in laboratory experiments. However, “Dengue virus 1 structural proteins” is a grouping, not a single molecule or unified target, so is_incorrect should be set to true for target standardization purposes (preferred canonical forms should be for individual proteins such as “Dengue virus envelope protein,” “Dengue virus capsid protein,” etc.)[3]. If you require structured data for each individual protein (capsid, prM/M, or E), it is best to query those specifically.

Other names

Dengue structural proteinDengue virus type 1 structural proteinsDENV1 structural proteinsDengue virus capsid proteinDengue virus envelope proteinDengue virus membrane protein

Inhibition of capsid protein dimerization (ST-148) - Inhibition of envelope protein-mediated membrane fusion (various small molecules, including 3-110-22 and others)[3]