Target intelligence / Profile preview

Dental Plaque Bacteria

Molecular classification
Microbial community, Biofilm
01

Overview

Dental plaque bacteria represent the diverse microbial community forming a biofilm on tooth surfaces. These bacteria metabolize dietary carbohydrates, producing acids that demineralize enamel, leading to caries. Specific species like Streptococcus mutans and Porphyromonas gingivalis are key pathogens. Effective management involves disrupting the biofilm through hygiene practices and antimicrobial agents, while novel therapies target specific pathogens without harming beneficial bacteria.

Other names
Dental biofilmOral microbiome (in context of plaque)Plaque bacteria
02

Mechanism of action

Antibiotics and antiseptics disrupt bacterial cell walls or metabolic processes. Fluoride strengthens enamel and inhibits bacterial enzymes. Enzyme inhibitors target biofilm formation.

03

Biological functions

Metabolism of dietary carbohydratesAcid productionBiofilm formationAdhesion to tooth surfacesProduction of inflammatory compounds
04

Disease associations

Dental cariesPeriodontal diseaseGingivitis
05

Safety considerations

Antibiotic resistanceDisruption of oral microbiome balanceStaining of teeth (e.g., Chlorhexidine)Potential for systemic effects with some antimicrobials
06

Interacting drugs

Antibiotics (e.g., Chlorhexidine, Tetracycline)

3 more in the full profile.

07

Biomarkers

Specific bacterial species abundance (e.g., S. mutans, P. gingivalis)pH levels in plaqueInflammatory markers in gingival crevicular fluid

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