Target intelligence / Profile preview

Dental Pulp Stem Cell (DPSC)

Target: DPSC
Molecular classification: Mesenchymal Stem Cell, Adult Stem Cell

Overview

Dental pulp stem cells (DPSCs) are a type of adult stem cell found within the dental pulp of teeth. They are mesenchymal stem cells with high self-renewal, rapid proliferation, and multi-lineage differentiation potential, capable of differentiating into osteoblasts, chondrocytes, adipocytes, neural cells, and other cell types. They are being explored for therapeutic applications in tissue engineering, bone repair, neuroregeneration, and immunomodulation.

Other names: DPSCs

Biological functions

Self-renewalProliferationMulti-lineage differentiationTissue regenerationImmunomodulation

Disease associations

Dental tissue defectsBone defectsNeurodegenerative diseasesImmune disorders

Safety considerations

Potential for uncontrolled proliferationOff-target differentiationImmunogenicity (though lower than BM-MSCs)

Biomarkers

CD73CD90CD105STRO1SSEA4OCT3/4NANOGSOX2

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