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Dentatorubral-pallidoluysian atrophy pseudogene

Molecular classification: Pseudogene

Overview

The dentatorubral-pallidoluysian atrophy pseudogene (ENSG00000230026) is a non-functional genetic element with high sequence homology to the human *ATN1* gene, but it does *not* produce a functional protein. Pseudogenes are common features in genomic DNA, typically arising from duplication or mutation of protein-coding genes, and do not contribute to disease or drug response. By contrast, the **functional ATN1 gene** is associated with dentatorubral-pallidoluysian atrophy when a CAG trinucleotide repeat expansion occurs, but the pseudogene itself is biologically inert and not relevant to therapy or diagnostics.

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