Target intelligence / Profile preview

Deoxyribonucleic Acid (None)

Target
None
Molecular classification
Nucleic Acid
01

Overview

Deoxyribonucleic acid (DNA) is the hereditary material in almost all living organisms, responsible for storing and transmitting genetic information. It is a nucleic acid composed of two long chains (strands) of nucleotides that coil around each other to form a double helix structure. DNA encodes genetic instructions used in development, functioning, growth, and reproduction. Genes within DNA specify sequences for proteins or functional RNAs. Most cellular DNA resides in the nucleus (“nuclear DNA”), but some exists in mitochondria (“mitochondrial DNA”).

02

Mechanism of action

Varies widely; includes direct DNA damage (e.g., alkylation, strand breaks), interference with DNA replication or transcription, alteration of gene expression via oligonucleotides or gene editing, and stimulation of immune responses (DNA vaccines).

03

Biological functions

Genetic Information StorageHeredityEncoding genetic instructions for development, functioning, growth, and reproduction.
04

Disease associations

CancerGenetic DisordersInfection (viral integration)Other (aging, cellular senescence)
05

Safety considerations

Off-target effects (gene editing)Insertional mutagenesis (gene therapy)Development of resistance (chemotherapy)Genotoxicity (alkylating agents)Immune response (DNA vaccines, oligonucleotide therapeutics)
06

Interacting drugs

Chemotherapeutic agents (e.g., alkylating agents, intercalating agents)

4 more in the full profile.

07

Biomarkers

Mutations in specific genes (e.g., tumor suppressor genes, oncogenes)Microsatellite instability (MSI)Copy number variations (CNVs)DNA methylation patternsTelomere lengthCirculating tumor DNA (ctDNA)

Beyond the preview

Go deeper on Deoxyribonucleic Acid (None).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Drug pipeline

Full profile access

Explore the programs pursuing this target and their development progress.

  • Drug candidates
  • Developers
  • Development stage

Clinical trials

Full profile access

Follow the clinical studies evaluating therapies directed at this target.

  • Trial design
  • Status
  • Readouts

Competitive landscape

Full profile access

Compare approaches across drug candidates, modalities, and indications.

  • Programs
  • Modalities
  • Indications

Literature & evidence

Full profile access

Investigate the research and source evidence behind target biology and development.

  • Publications
  • Sources
  • Analysis

Patents

Full profile access

Explore patent activity around therapies and technologies addressing this target.

  • Patents
  • Assignees
  • Technologies

Research & analysis

Full profile access

Connect target biology, drug development, and emerging evidence in your research.

  • Biology
  • Development news
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Deoxyribonucleic Acid (None).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call