House Dust Mite Allergen

House dust mite allergens are proteins found in the feces and body parts of house dust mites. These allergens trigger IgE-mediated Type I hypersensitivity reactions, leading to symptoms of allergic rhinitis, asthma, and atopic dermatitis. Key allergens include Der p 1, Der f 1, Der p 2, Der f 2, and Der p 7. Der p 1 is a cysteine protease that disrupts epithelial barriers. Group 2 and 7 allergens share structural similarities with proteins involved in innate immunity pathways.

Other names

Der p 1Der f 1Der p 2Der f 2Der p 7Der f 7

Antihistamines block histamine receptors to reduce allergy symptoms. Corticosteroids reduce inflammation. Immunotherapy desensitizes the individual by gradually increasing exposure to the allergen.