destrin (actin depolymerizing factor) pseudogene

The destrin pseudogene (ENSG00000258540), annotated as "destrin (actin depolymerizing factor) pseudogene," is a DNA segment related in sequence to the functional gene *destrin (DSTN)* but has accumulated disabling mutations (such as premature stop codons and frameshifts) that prevent it from encoding a functional protein product[1][2][4]. Pseudogenes typically result from duplication or retrotransposition of a functional gene followed by loss of regulatory capacity and/or coding potential[2][4]. The destrin pseudogene is not expressed as a functional protein and is not classified as a receptor, enzyme, transporter, or transcription factor. It is considered genomic “junk DNA,” and is generally not associated with disease or therapeutic intent[2][4]. The presence of pseudogenes can sometimes confound genetic studies due to sequence similarity with functional genes, but they are not active drug targets, do not serve established biological functions, and do not interact with drugs[4].

Other names

destrin pseudogeneactin depolymerizing factor pseudogeneDSTN pseudogene