Target intelligence / Profile preview

DET1 and DDB1 associated 1 pseudogene (ENSG00000258509)

Target
ENSG00000258509
Molecular classification
Pseudogene
01

Overview

DET1 and DDB1 associated 1 pseudogene (ENSG00000258509) is classified as a pseudogene, meaning it is a DNA sequence similar to a protein-coding gene but is generally nonfunctional due to mutations, loss of coding capability, or regulatory elements required for expression[4][2][5]. It is related by sequence homology to the functional DET1 and DDB1 associated 1 gene (DDA1), but does not encode a functional protein and is not considered a therapeutic target, receptor, enzyme, transporter, or transcription factor[5][2][4]. Pseudogenes can sometimes participate in gene regulation, but there is no published evidence that ENSG00000258509 has any regulatory, biological, or clinical function[5][4][6]. In summary, this entry represents a nonfunctional genomic relic, not a molecular target for therapy or diagnostics. If you have questions about the functional DDA1 protein (DET1-DDB1-associated 1), which is involved in ubiquitination and chromatin regulation, please specify, as that is a distinct, functional gene/protein[1][3][7].

Other names
DET1 And DDB1 Associated 1 pseudogeneDDA1 pseudogene
02

Mechanism of action

None (not a protein, not a drug target)

03

Biological functions

Pseudogenes are generally nonfunctional—meaning they do not encode active proteinssome pseudogenes can have regulatory roles, such as influencing gene expression via RNA mechanisms, but for ENSG00000258509, there is no evidence of such function
04

Disease associations

Pseudogenes can sometimes play regulatory roles in disease, but there is no specific evidence for ENSG00000258509 participating in any disease process

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