Detoxification

Detoxification refers to the physiological or medicinal process by which toxic substances are removed or neutralized from a living organism. In humans, this process primarily involves organs such as the liver and kidneys. The liver metabolizes toxins into less harmful compounds for excretion via bile or urine using specialized enzymes like cytochrome P450. The kidneys filter blood to remove waste products through urine. Additional systems involved include the lungs (removal via respiration), skin (elimination through sweat), lymphatic system (transport of waste), and digestive tract[1][3][5]. At the cellular level, detoxification includes enzymatic processes that reduce toxicity or transport toxins away from sensitive tissues[8][9]. In medicine, "detoxification" can also refer to interventions managing acute intoxication or withdrawal in substance use disorders[6]. While essential for health maintenance and protection against environmental and metabolic toxins, "detoxification" itself is not a specific molecular target but rather an umbrella term describing multiple biological pathways. Note: There is something incorrect with using "Detoxification" as a therapeutic target name—it describes a broad biological process involving many molecules/enzymes/receptors rather than any single defined molecular entity suitable for drug targeting. For structured data purposes, it should be replaced with specific targets such as "Cytochrome P450 enzyme," "Glutathione S-transferase," etc., depending on context[1][3].

Other names

DetoxicationDetox