Developmental pluripotency associated 2 pseudogene

The developmental pluripotency associated 2 pseudogene (LOC100421141; ENSG00000250006) is a pseudogene related to the protein-coding gene DPPA2 (Developmental pluripotency associated 2), but unlike its functional paralog, it does not encode a functional protein product or act as a classic therapeutic target. Pseudogenes are segments of DNA similar to normal genes but typically nonfunctional and not translated into protein. LOC100421141 is described on GeneCards as a pseudogene and not a protein-coding gene, thus it does not have enzymatic, receptor, or transporter activity, nor does it have known roles in biological processes or diseases. Pseudogenes may sometimes have regulatory roles, but such functions are currently unknown or undocumented for this particular pseudogene. No drugs, disease associations, molecular mechanisms, or clinical biomarkers are associated with this gene. The parent protein-coding gene, DPPA2, is involved in pluripotency and chromatin binding, but these functional annotations do not apply to the pseudogene variant. It is a noncoding pseudogene, not a therapeutic target, with no known biological function or disease association, and is not involved in drug interactions or used as a biomarker. For functional studies and drug targeting, only the protein-coding gene DPPA2 (not its pseudogene) is relevant.

Other names

LOC100421141ENSG00000250006developmental pluripotency associated 2 pseudogene