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Target intelligence / Profile preview
Developmental pluripotency associated 3 pseudogene (DPPA3P3)
- Target
- DPPA3P3
- Molecular classification
- Other (pseudogene)
01
Overview
The developmental pluripotency associated 3 pseudogene (ENSG00000275017, also known as DPPA3P3 or DPPA2P3) is annotated as a pseudogene in the human genome. Pseudogenes are non-coding DNA sequences that resemble protein-coding genes but have lost their protein-coding ability due to mutations or deletions. This particular pseudogene is related to the developmental pluripotency associated 3 (DPPA3) gene, which is important in early embryonic development and epigenetic reprogramming. However, ENSG00000275017 does not encode a functional protein and thus is not implicated as a direct therapeutic target or receptor[1]. Its biological significance, if any, may be restricted to regulatory or evolutionary functions and does not fit typical drug target or biomarker criteria. Important clarification: If you intend to evaluate DPPA3 (Stella/PGC7), that is a protein-coding gene involved in the regulation of DNA methylation, chromatin remodeling, and zygotic genome activation during early embryonic development[3]. However, ENSG00000275017 specifically refers to its pseudogene, which is not a drug target.
- Other names
- Developmental pluripotency associated 2 pseudogene 3DPPA2P3DPPA3P3
02
Mechanism of action
None.
03
Biological functions
Other (as a pseudogene, it does not have direct biological function as proteins do; parent gene DPPA3 is involved in epigenetic regulation and maintaining pluripotency, but this pseudogene does not encode a functional product)
04
Disease associations
Other (no direct disease role established; pseudogenes can have regulatory or evolutionary significance, but no evidence supports a direct role in disease for this entry)
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