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DPPA3P3 (developmental pluripotency associated 3 pseudogene 3) is a human pseudogene, meaning it is a genomic DNA sequence similar to the functional DPPA3 gene but non-coding and non-functional. While the closely related gene DPPA3 is involved in pluripotency regulation, DNA methylation, and early embryogenesis, DPPA3P3 does not produce a functional protein and has no recognized biological activity or disease association. It is annotated as a pseudogene by HGNC (HGNC:49062) and is primarily of interest for genomic and evolutionary studies rather than as a therapeutic target[2][3][5][8]. Key note: - This record is sometimes confused with the protein-coding DPPA3 gene, which has clear biological function and disease associations[1][6][7]. - There is nothing incorrect with the name or annotation, but it is important to distinguish DPPA3P3 (the pseudogene) from DPPA3 (the functional gene). - As a pseudogene, DPPA3P3 is not considered a drug target, receptor, enzyme, or similar entity.
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