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Target intelligence / Profile preview
DHDDS antisense RNA 1 (DHDDS-AS1)
- Target
- DHDDS-AS1
- Molecular classification
- Other (long non-coding RNA)
01
Overview
DHDDS antisense RNA 1 (DHDDS-AS1) is a long non-coding RNA gene located antisense to the DHDDS (dehydrodolichyl diphosphate synthase subunit) gene. As an antisense transcript, it may regulate the expression of DHDDS or play a role in RNA-mediated gene regulatory mechanisms, but its precise function, molecular mechanism, and clinical significance have not been characterized in current literature[3][4]. No evidence supports its classification as a direct therapeutic target such as an enzyme, receptor, or transporter. Current data sources (GeneCards, BioGPS, NCBI gene records) provide only basic gene annotation and transcript information for DHDDS-AS1, with no functional studies, disease association, or known interacting drugs, distinguishing it from the adjacent protein-coding DHDDS gene[3][4][6].
- Other names
- DHDDS-AS1LOC124903883
02
Biological functions
Not specifically characterized. Antisense RNAs often regulate the expression of their sense counterparts, in this case possibly the DHDDS gene.
03
Disease associations
Currently, no direct disease associations have been established for DHDDS-AS1, but DHDDS (the protein-coding gene) is associated with retinitis pigmentosa and neurodevelopmental disorders.
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