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Dietary composition modification refers to deliberate changes in the relative amounts or sources of dietary macronutrients (proteins, carbohydrates, fats) and/or micronutrients in food, with the aim to influence biological functions and health outcomes. This intervention can alter gut microbiota composition, change rates of glycan degradation and amino acid metabolism, and affect gene expression via mechanisms such as epigenetic modifications (histone modifications and DNA methylation). Dietary composition modifications are widely used in research and clinical practice as strategies for prevention and management of nutrition-related diseases, but they do not describe a molecular target or receptor and are not appropriate as canonical entries for molecular target databases[4][6][8]. In summary, "Dietary composition modification" is an intervention approach, not a molecule, protein, receptor, or gene, and thus does not fit the format required for molecular target/receptor cataloging.
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