Target intelligence / Profile preview

Dietary fiber-mediated cholesterol reduction (None)

Target
None
Molecular classification
Other
01

Overview

Dietary fiber, particularly soluble fiber, plays a crucial role in lowering cholesterol levels by binding bile acids, altering lipid metabolism, and promoting beneficial fermentation products. This process helps in reducing the risk of cardiovascular disease by lowering LDL cholesterol levels.

Other names
Cholesterol-lowering effect of dietary fiberSoluble fiber-mediated cholesterol reduction
02

Mechanism of action

Binding bile acids in the intestine, preventing their reabsorption. Promoting the production of short-chain fatty acids during fermentation, which can reduce cholesterol synthesis in the liver. Slowing down the digestion and absorption of fats and cholesterol.

03

Biological functions

Lipid metabolismCholesterol regulationCardiovascular health
04

Disease associations

Cardiovascular disease
05

Safety considerations

High fiber intake can lead to gastrointestinal side effects, such as bloating and gas, especially in individuals with irritable bowel syndrome.
06

Interacting drugs

psyllium

2 more in the full profile.

07

Biomarkers

LDL cholesteroltotal cholesterol

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