Digestive function regulation

Digestive function regulation refers to the coordinated control of digestive processes—motility, secretion of enzymes, acid, bile, and absorption—through hormonal (e.g., cholecystokinin, secretin, gastrin, GLP-1, GIP) and neural (enteric nervous system, autonomic input) mechanisms. These actions are mediated by specific molecular targets, including GPCRs and receptors present on digestive tract cells, and contribute to the proper breakdown, absorption, and assimilation of nutrients[1][2][3][6][7]. Disruption of these regulatory mechanisms underlies various digestive disorders and metabolic diseases.

Drugs modulate individual endpoints—acid secretion, enzyme release, motility—by targeting specific receptors or channels within this regulatory system[2][5][7].