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DIP2A intronic transcript 1 (non-protein coding) (DIP2A-IT1)
- Target
- DIP2A-IT1
- Molecular classification
- Other (Long noncoding RNA, lncRNA)
01
Overview
DIP2A intronic transcript 1 (DIP2A-IT1) is a long noncoding RNA (lncRNA) transcribed from an intronic region of the DIP2A gene on human chromosome 21. It does not encode a protein or micropeptide and is localized in the cytosol. DIP2A-IT1 has been identified as upregulated in osteosarcoma tissue relative to normal bone and is thus implicated in cancer biology. Its detailed biological functions, molecular partners, and clinical relevance as a biomarker or therapeutic target remain unclear, as limited functional characterization exists. There is no evidence to date that DIP2A-IT1 is a therapeutic target such as a receptor, enzyme, transporter, or similar modality[1][3][7].
- Other names
- DIP2A-IT1DIP2A intronic transcript 1
02
Biological functions
Possible regulation of gene expression at the RNA level
03
Disease associations
Cancer (upregulated in osteosarcoma)
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