Target intelligence / Profile preview

Diphtheria Toxin Antigen (None)

Target
None
Molecular classification
Exotoxin, Enzyme
01

Overview

Diphtheria toxin antigen refers to the protein exotoxin produced by *Corynebacterium diphtheriae*. The toxin is responsible for the symptoms and pathology of diphtheria, a serious infectious disease characterized by sore throat, fever, and necrosis of respiratory tissue. It inhibits protein synthesis by ADP-ribosylating elongation factor 2 (EF2).

02

Mechanism of action

ADP-ribosylates EF2, inhibiting protein synthesis

03

Biological functions

Protein synthesis inhibitionCell deathADP-ribosylation of EF2
04

Disease associations

InfectionDiphtheria
05

Safety considerations

ToxicityImmunogenicity
06

Interacting drugs

Diphtheria antitoxin

1 more in the full profile.

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