Drug pipeline
Full profile accessExplore the programs pursuing this target and their development progress.
- Drug candidates
- Developers
- Development stage
Target intelligence / Profile preview
DIS3L antisense RNA 1 (DIS3L-AS1)
- Target
- DIS3L-AS1
- Molecular classification
- Long noncoding RNA (lncRNA), Other (Non-protein coding RNA)
01
Overview
DIS3L antisense RNA 1 (DIS3L-AS1) is a long noncoding RNA gene transcribed antisense to the DIS3L locus, which encodes a cytoplasmic exosome 3'-5' exonuclease protein. While DIS3L itself is an essential exoribonuclease in mRNA turnover and RNA quality control[3][5], DIS3L-AS1 is a noncoding transcript with as yet poorly understood function. Antisense lncRNAs often regulate expression of their cognate gene either by transcriptional interference or RNA-mediated mechanisms, but the specific biological and disease relevance of DIS3L-AS1 has not been characterized in main databases or research literature. Current evidence places DIS3L-AS1 among the large class of lncRNAs with hypothesized regulatory functions, not as a classic drug or therapeutic target. This distinguishes it from the protein-coding DIS3L gene, which encodes a cytoplasmic exoribonuclease involved in mRNA metabolism and embryonic development[3][5].
- Other names
- DIS3L-AS1
02
Biological functions
Transcriptional regulationRegulation of gene expressionOther (specific biological functions for DIS3L-AS1 are not well characterized in the cited literature)
03
Disease associations
Other (No confirmed major role in cancer, inflammation, or other diseases in main sources; any association would be speculative without evidence)
Beyond the preview
Go deeper on DIS3L antisense RNA 1 (DIS3L-AS1).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Clinical trials
Full profile accessFollow the clinical studies evaluating therapies directed at this target.
- Trial design
- Status
- Readouts
Competitive landscape
Full profile accessCompare approaches across drug candidates, modalities, and indications.
- Programs
- Modalities
- Indications
Literature & evidence
Full profile accessInvestigate the research and source evidence behind target biology and development.
- Publications
- Sources
- Analysis
Patents
Full profile accessExplore patent activity around therapies and technologies addressing this target.
- Patents
- Assignees
- Technologies
Research & analysis
Full profile accessConnect target biology, drug development, and emerging evidence in your research.
- Biology
- Development news
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on DIS3L antisense RNA 1 (DIS3L-AS1).