Disc regeneration

Disc regeneration refers to strategies aiming to restore the structure and function of the intervertebral disc, particularly in the setting of age- or injury-related degeneration. Biological approaches include the use of cell therapy (e.g., mesenchymal stem cells), growth factor delivery, and gene therapy to promote regeneration of the disc's extracellular matrix and functional tissue. The disc microenvironment presents unique challenges due to low nutrient and oxygen supply, mechanical loading, and pro-inflammatory conditions that accompany degeneration. Current research focuses on overcoming these barriers to achieve meaningful tissue restoration and prevent or reverse degenerative disc disease[1][3][5][7].

Other names

Intervertebral disc regenerationIVD regenerationRegeneration of intervertebral disc