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The term “diseased lung tissue” broadly refers to any portion of the lung that is affected by disorders such as infection, inflammation, neoplasia (tumor), fibrosis, or other pathological processes. The cellular and molecular makeup of diseased lung tissue can vary widely, including inflammatory cells, proliferating epithelial cells, fibrotic tissue, neoplastic (tumor) cells, and disrupted normal lung architecture. Scientific and medical literature instead focuses on precise targets within diseased lung tissue (such as “epidermal growth factor receptor,” “type II pneumocyte,” “M2 macrophage,” etc.) or on molecular pathways that are dysregulated in specific diseases such as chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), lung cancer, or infection[1][2]. Therefore, “diseased lung tissue” is a descriptive, anatomical term rather than a molecular or druggable target, and cannot be mapped to the requested structured information for a target molecule or receptor.
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