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Divergent protein kinase domain 1A (DIPK1A)
- Target
- DIPK1A
- Molecular classification
- Protein kinase domain family (DIPK family), Cysteine-rich type II transmembrane protein
01
Overview
Divergent protein kinase domain 1A (DIPK1A) is a member of the FAM69 family of cysteine-rich type II transmembrane proteins, predicted to reside in the membrane of the endoplasmic reticulum[2][4][5]. The gene is located on human chromosome 1p22.1, and several transcript variants (isoforms) have been described[2][5][7]. The molecular and biological function of DIPK1A remains uncharacterized; no experimental evidence links it to well-defined cellular processes or disease mechanisms. While genetic associations connect DIPK1A to Diamond-Blackfan anemia 6 and interatrial communication, these links are not supported by direct functional studies[2][7]. No drugs are currently known to target DIPK1A, and there is no established use of DIPK1A as a biomarker or therapeutic target at this time[2][5][8].
- Other names
- FAM69AFLJ23493Protein FAM69AFamily with sequence similarity 69 member AENSG00000154511
02
Mechanism of action
None identified, due to the absence of interacting agents
03
Biological functions
Localizes to the endoplasmic reticulum membraneExact function is unknown; no experimental evidence supports specific biological processesNo assigned functions in signal transduction, proliferation, or apoptosis due to lack of data
04
Disease associations
Diamond-Blackfan anemia 6Interatrial communication (linked via genetic association, not direct functional evidence)No established role in cancer, inflammation, neurodegeneration, or other major disease categories
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