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DLG2 antisense RNA 2 (DLG2-AS2)

Target
DLG2-AS2
Molecular classification
Long non-coding RNA (lncRNA), Antisense RNA
01

Overview

DLG2 antisense RNA 2 (DLG2-AS2) is a long non-coding RNA (lncRNA) transcribed from the opposite strand of the DLG2 gene locus. It does not encode a protein but is thought to participate in the regulation of gene expression, possibly involved in cis or trans regulation of neighboring or distant genes. DLG2-AS2, like other antisense lncRNAs, may play roles in tumorigenesis and neurodevelopment, although current evidence for DLG2-AS2 specifically is extremely limited. Closely related transcripts such as DLG2-AS1 have been studied in the context of cancer (notably lung adenocarcinoma) as potential tumor suppressors and biomarkers, but there is no direct functional or disease role established for DLG2-AS2 itself, nor evidence for it as a direct therapeutic target or drug-interacting entity.

Other names
DLG2-AS2AP001825.2
02

Biological functions

Gene expression regulationPotential tumor suppressor function (in lung adenocarcinoma)
03

Disease associations

Cancer (particularly lung adenocarcinoma as a potential biomarker)
04

Biomarkers

DLG2-AS1 (potential biomarker for lung adenocarcinoma)

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