DNA base

DNA bases—also known as nucleotide bases, nucleobases, or nitrogenous bases—are the fundamental building blocks that make up the genetic code within deoxyribonucleic acid (DNA). There are four canonical DNA bases: adenine (A), thymine (T), guanine (G), and cytosine (C)[1][2][3][9]. These molecules form specific pairs through hydrogen bonding—adenine with thymine and guanine with cytosine—which is essential for the double helix structure of DNA[1][5]. The sequence of these bases encodes genetic information used in protein synthesis and cellular function[2][6]. While individual drugs may target processes involving these molecules, "DNA base" itself is not a therapeutic target like a receptor or enzyme; rather, it is a chemical component within larger biological macromolecules. The term "DNA bases" refers to multiple small molecules rather than a single defined molecular entity. Note: This entry is marked as incorrect because "DNA bases" does not refer to a single therapeutic target but instead describes several small molecule components found within nucleic acids. It lacks specificity required for structured drug-target databases.

Other names

nucleotide basenucleobasenitrogenous base

Inhibition of DNA synthesis by incorporation of analogs Induction of mutations or strand breaks by chemical modification