Target intelligence / Profile preview

DNA elongation

Molecular classification
Other (DNA replication process)
01

Overview

"DNA elongation" refers to the stage within DNA replication where enzymes, primarily DNA polymerases, synthesize new DNA strands by sequentially adding nucleotides complementary to the template strands. During this phase, the replication machinery extends from a primer—usually an RNA segment—provided by primase. Elongation occurs concurrently at replication forks, with continuous synthesis on the leading strand and discontinuous synthesis producing Okazaki fragments on the lagging strand. This process ensures accurate genome duplication and is essential for cell division in all life forms[1][2][3].

Other names
DNA synthesis elongationDNA replication elongationelongation phase of DNA replication
02

Biological functions

DNA replicationGenome duplicationCell cycle progression
03

Disease associations

Other (dysfunction in DNA elongation can contribute to genomic instability and diseases such as cancer, but the elongation phase itself is not a direct disease target)[1][2][3].

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