DNA or RNA (within cancer cell) (null)

DNA and RNA within cancer cells represent the fundamental molecules encoding, transmitting, and regulating all genetic information[2][4][5]. DNA (deoxyribonucleic acid) stores the cell's hereditary information, while RNA (ribonucleic acid) transcribes and transmits the DNA code for the synthesis of proteins or regulatory functions[2][3][6]. Mutations or epigenetic dysregulation of DNA and RNA contribute critically to cancer development, driving aberrant cell proliferation, evasion of apoptosis, and therapeutic resistance[4][7]. Modern cancer therapies target specific DNA mutations, gene fusions, epigenetic modifications, or RNA transcripts, either directly (e.g., antisense oligonucleotides, siRNA) or by using drugs that damage or modify DNA/RNA and their associated regulatory proteins[1][3][6]. Given their ubiquity and centrality, "DNA/RNA within cancer cell" is not a single therapeutic target, but alterations in DNA and RNA provide both disease causality and actionable avenues for diagnostics and drug development.

Other names

genetic materialnucleic acidsgenome (for DNA)transcriptome (for RNA)chromatin (for DNA in complex with proteins)

Induce DNA damage leading to apoptosis\nInhibit DNA or RNA synthesis\nModify gene expression by targeting epigenetic marks\nSilence or degrade specific RNA transcripts\nModulate splicing or translation of mRNAs