DNA Polymerase Activity

DNA polymerase activity during S-phase replication refers to the enzymatic processes responsible for synthesizing new DNA strands during the cell cycle's synthesis phase. This activity is crucial for cell proliferation and is mediated by various DNA polymerases, including Pol δ and Pol ε in eukaryotes. These enzymes ensure the fidelity of DNA replication by accurately incorporating nucleotides into the growing DNA strand. Dysregulation or mutations in DNA polymerases can lead to genetic instability and contribute to diseases like cancer.

Other names

DNA PolymeraseDNA Replication Enzymes

Inhibition of DNA synthesis, interference with DNA replication fidelity