DNA synthesis and cell division

"DNA synthesis and cell division" collectively refer to the tightly regulated processes by which living cells copy their genomic DNA and evenly distribute it to daughter cells during cell division. DNA synthesis (replication) is orchestrated by multiple enzymes including DNA polymerases, helicases, primases, ligases, and accessory proteins, predominantly occurring during the S phase of the cell cycle. Cell division follows, involving mitosis (in somatic cells) or meiosis (in germ cells), ensuring tissue growth, development, maintenance, and heredity[1][2][3][4][5]. Malfunctions in these processes underlie cancer and various genetic diseases, and many anticancer therapies target enzymes and proteins essential for DNA synthesis or mitotic progression rather than this non-specific concept itself. Key clarification: This is not a canonical drug target but describes overarching essential processes. Actual drug targets within "DNA synthesis and cell division" include DNA polymerases, topoisomerases, cyclin-dependent kinases, and mitotic spindle proteins, among others. Each of those would have their own structured information. The queried phrase itself is too broad and thus "is_incorrect: true."

Other names

DNA replication and mitosisDNA replication and cell divisionDNA duplication and cell division