DnaJ homolog, subfamily B, member 14 pseudogene

This gene, "DnaJ homolog, subfamily B, member 14 pseudogene" (ENSG00000259924), is a pseudogene in the human genome and does not encode a functional protein. Unlike its paralog DNAJB14, which acts as a co-chaperone in protein folding, the pseudogene form does not contribute to known biological functions, molecular pathways, or therapeutic targeting[3][1]. It is listed in databases solely as a pseudogene without evidence of protein production or direct biological or disease relevance[3]. Note on potential confusion: The functional paralog, DnaJ heat shock protein family (Hsp40) member B14 (DNAJB14), is a bona fide protein-coding gene with recognized chaperone functions and some disease associations, but ENSG00000259924 specifically refers to the non-functional pseudogene version[1][3]. Any attempt to treat ENSG00000259924 as a therapeutic target would be incorrect.